Condition-Based Probabilistic Safety Assessment (CB-PSA) makes use of inspections and monitoring information on Systems, Structures, and Components (SSCs) to update risk quantities. In this paper, we show the benefits of exploiting the condition-based estimates for taking maintenance decisions on a SSC undergoing multiple degradation mechanisms. To develop the method, we make reference to a spontaneous Steam Generator Tube Rupture (SGTR) Accident Scenario in a Nuclear Power Plant (NPP). The SG is susceptible to multiple degradation mechanisms, i.e., Stress Corrosion Cracking (SCC) and pitting. Tube plugging and Water Lancing and Chemical Cleaning (WL-CC) can be performed, before leading to a SGTR accident. Decisions must be taken on the maintenance strategy to perform at each inspection cycle. Results of a case study regarding SGTR show that the decisions based on the risk estimates provided by a CB-PSA approach allow controlling the SGTR risk at minimum maintenance cost.