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            <title xml:lang="en">Coupled heat and resource allocation network design considering multi-contaminants, properties and non-isothermal mixin</title>
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                <term xml:lang="en"> Multiproperties</term>
                <term xml:lang="en"> Multicontaminants</term>
                <term xml:lang="en"> Non-isothermal mixing</term>
                <term xml:lang="en"> MILP</term>
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              <p>This paper introduces a new approach for the design of heat-integrated resource allocation network with a minimum total annualized cost. In a first step, a MILP model determines the minimum fresh resource flow rate necessary to satisfy all mass-related constraints. The model takes into account multicontaminants and multiproperties cases. It also includes the possibility to use several fresh resources (with different characteristics) and several waste sinks (with different limitations). Then, a second MILP model is used to design an optimal heat integrated resource allocation network. The objective function includes fresh resource, waste discharge and utilities costs. The fresh resource flow rate search space is restrained thanks to the first model results. The heat integration is realized with a modified transshipment model, where the temperature scale is discretized in order to account for non-isothermal mixing. Technical constraints, expressing real on site industrial restrictions, are introduced to lead the optimal solution towards a more realistic network. The methodology is demonstrated on a literature case study. It shows the interest of simultaneous optimization of both heat and resource compared to a sequential approach. </p>
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